A deadly storm that's left a trail of wreckage across a vast swath of the United States continued to slam the Northeast and Great Lakes regions with heavy snow, rain and wind on Thursday, knocking out power, closing schools and disrupting travel in major cities.

Meteorologists expect 1-2 feet of snow to over New England, especially in Maine, New Hampshire, Vermont and northeast New York, according to the National Weather Service. The combination of pummeling snow and gusty winds led to whiteout conditions and snow-covered roads in some areas. Many schools and government offices across the region were closed.

"Please stay off the roads today if you can," said Maine Gov. Janet Mills in a post on X. "If you must drive, take it slowly, and always give plenty of room to first responders, plow trucks, and utility crews."

The weather service issued flood advisories across parts of Illinois, east through Virginia and up to Rhode Island, including Washington D.C. and New York City. Over 3 inches of rain had fallen in parts of New Jersey as of Thursday morning. The same storm impacted the Great Lakes, with several inches of snow reported in Wisconsin and Michigan.

Meanwhile, parts of California, Nevada, Utah, Arizona, Colorado and New Mexico were under weather advisories warning of strong winds, coastal rain and snow in areas of high elevation. A front moving east over the northern High Plains, Great Basin and Southern California regions will linger over the Sierra Nevada Mountains through Saturday, while snow is anticipated to lash the Rockies into the weekend.

Hundreds of thousands without power; flights canceled

More than 500,000 homes and businesses were without power across the Northeast, especially in Maine, where over 300,000 utility customers were without power as of early Thursday, according to a database maintained by USA TODAY. The Great Lakes region was not spared: Michigan and Wisconsin reported over 60,000 outages.

Airports in Boston, New York and New Jersey reported the most disruptions, with about 100 cancellations and 150 delays, according to FlightAware, a flight tracking website.

Damage assessments, clean up underway in parts of central, eastern US

The large storm system, which has walloped the nation with severe weather conditions since the weekend, spun up tornadoes in Illinois, Kentucky, Ohio, Tennessee, Alabama and Georgia this week, damaging businesses and leveling homes. In areas as far south as Florida, strong winds toppled utility poles and snapped trees. Throughout the Midwest, floodwaters trapped cars in roadways and left people stranded for hours.

"It's devastating," said Sunbright Mayor Karen Melton on Wednesday after a tornado ripped through the small Tennessee city, about an hour northwest of Knoxville. Though there were no deaths of injuries, the damage was immense. "We had a young mother and father holding their babies, an infant and a 4-year-old (when) the tornado ripped the roof of their apartment. ... It was just horrific and sad. But they were safe, she had some scratches, but the babies were safe. That was just a major blessing."

In northern West Virginia, a mudslide washed out over 200 tombstones at a cemetery in Wheeling, a small city at the foothills of the Appalachian Mountains, reported CBS42. The cemetery, which was closed Thursday, is home to thousands of graves, some of which date back to the Civil War.

In Indiana, the storm destroyed homes throughout the Evansville area, including the city's wartime museum, which had to cancel all events and close because it had "heavily sustained damage." Photos posted on the museum's Facebook page show caved in ceiling tiles and exposed insulation.

Authorities in Georgia continued the clean up effort following a pair of tornadoes that struck the Atlanta metro area and Crisp County, near the center of the state, late Tuesday night, according to the National Weather Service. In Crisp County, where the tornado had max winds of up to 100 mph, some 36 homes were either damaged or completely destroyed.

"This is a dangerous situation: trees still being cut in the area, power lines still down, a lot of equipment moving back and forth," said Sheriff Billy Hancock in a video posted to Facebook on Thursday. "There's still plenty of work to be done."

Officials tie several deaths to powerful storm

At least four people died in Kentucky, Oklahoma and Pennsylvania because of the storm this week.

On Wednesday, two people – a 70-year-old man and an 82-year-old woman – died when their cars were crushed by fallen trees, multiple outlets reported. A young man in Campbell County, Kentucky, died in a traffic accident during Tuesday’s storms, Gov. Andy Beshear said at a news conference Wednesday.

On Monday, a 46-year-old unhoused woman in Tulsa, Oklahoma, died after seeking shelter in a storm drain  KJRH-TV reported.

Major California highway closed again after partial collapse

A major highway in Southern California that collapsed over the weekend when thunderstorms drenched the region has been closed again as more severe weather is forecast for the region.

The Monterey County Sheriff's Office in Salinas announced an evacuation order Wednesday morning for areas of Big Sur ahead of showers and thunderstorms that began Thursday and are anticipated to continue Friday. Officials said residents could evacuate on Highway 1 to the north before "a full road closure" where the collapse occurred last Saturday.

The road "slip out" happened during heavy rainfall that was fueled by the large weather system making its way across the country, which also brought damaging hail to the Midwest.

Contributing: Liz Kellar, Knoxville News Sentinel