Drew Barrymore went full throttle with her latest makeover.

The 49-year-old debuted a fierce blonde transformation on her eponymous daytime talk show June 6. And in true Drew fashion, she used one of her most iconic Y2K style moments as the inspiration for her drastic change.

In fact, she channeled her Charlie's Angels: Full Throttle premiere look from 2003, in which she rocked wavy blonde tresses, grunge makeup, a gray graphic tee that read, "My boyfriend is out of town" and black leather pants.

Drew's new transformation came courtesy of her beauty angels, hairstylist Chris Appleton and makeup artist Charlotte Tilbury.

"This is my chance to say nothing, do nothing," the Never Been Kissed actress said in a behind-the-scenes Instagram video posted June 6, "and just be the clay, and they get to mold it."  

After a few hours in glam, it was time for Drew to see the results. "Oh my god, that's me!" she gushed. "You just put a time machine in me. I feel like that girl again. I feel like I'm back at the Charlie's Angels 2 premiere."

But much like in her role Ever After: A Cinderella Story, her fairytale makeover had to come to an end. Once she wrapped filming her show, the blonde wig came off and so did her makeup.

"I cannot believe you brought me back 21 years ago," Drew told Chris, as he scrubbed her foundation off. "Good to know I could look like a Charlie's Angels again."

Chris added, "She's still got it!"

Not surprisingly, Drew's fans went wild over her transformation and even tried convincing her to ditch her signature reddish-brown hair.

"Time to go back to blonde," one Instagram user wrote, while another person replied, "Love the blonde, it really suits you."

Michelle Pfeiffer even chimed in, "Well hello blondie!!"

However, the best comment of all went to Sharon Stone, who loved Drew's overall edgy vibe. As she put it, "Love bug YOU LOOK GREAT MISS YOU FREAK XOXOXOXO."

Drew isn't the only star to turn heads with a new 'do. Keep reading to see all of the celebrity makeovers in recent months.

The Heads of State star debuted a drastic haircut—a shoulder-grazing bob—while attending a Bulgari event in Rome on May 20. 

In May 2024, the actress chopped her hair into a bob that many fans on social media said reminded them of one of the looks she sported as Mary Camden on the '90s series 7th Heaven.

The Transformers actress returned to her dark brown tresses and debuted a sassy bob in May 2024, a month after she dyed her hair blue to enter what she dubbed her "Jedi era."

At age 17, the daughter of the late Anna Nicole Smith debuted a new lob hairstyle overnight during 2024 Kentucky Derby weekend, which she attended with dad Larry Birkhead.

The singer debuted a lighter, shorter 'do in April 2024.

The Fashion Police alum debuted a blonde bombshell hair transformation May 8.

Back to blonde: Kim debuted a new platinum 'do in April 2024.

The Fenty Beauty founder debuted a bright blonde hair transformation April 17 while celebrating her latest Fenty x Puma collection in London.

The model debuted a bleach blonde pixie cut at the FRAME event April 4.

The Jennifer's Body star traded in her bubblegum pink tresses for a baby blue bob, which she debuted April 2.

Less than a month afer chopping her hair into a long bob, Zendaya debuted a honey blonde transformation at the Challengers premiere March 26.

The Great star ushered in spring with a fresh cut, as she debuted a long bob March 25.

The Mean Girls alum swapped out her signature blonde hair for a dark brunette transformation on March 18.

The Selling Sunset star looked completely unrecognizable after debuting a dramatic blonde transformation March 16.

The Fashion Police alum ditched her signature purple hair after six years, tinting it an icy silver in March 2024. 

The Dune actress debuted a shoulder-grazing bob at Essence's Black Women in Hollywood Awards March 7.

The Anyone But You star made a showstopping appearance at Miu Miu's fall/winter 2024-2025 show during Paris Fashion Week. For the March 5 event, she unveiled a dramatic long bob haircut.

To prepare for her upcoming role as  Jean Seberg, the 29-year-old debuted a bleached blonde pixie cut.

The Princess Diaries alum unveiled fringe bangs at the 2024 Film Independent Spirit Awards.

The star debuted a bangin' new style at the premiere of her friend Nicola Peltz Beckham's film Lola in February 2024.

The "On the Floor" singer made a dramatic hair change, as she debuted a chin-grazing bob cut at Schiaparelli's haute couture spring/summer 2024 show on Jan. 22.

In January 2024, a month after her prison release, the now-influencer shared a pic of herself sporting a shorter 'do.

Kylie Jenner traded in her dark locks for a pink 'do in January 2024.

In January 2024, the Dancing With the Stars personality shared a video of herself cutting her own hair. "Out with the old energy," she wrote, "and in with the new."

The Underworld actress took the plunge and went full blonde, while also debuting a short bob haircut.

The Daisy Jones & The Six actress debuted jet-black hair on Nov. 2.

The Flamin' Hot director recently showcased her dramatic transformation, debuting a choppy, layered bob on Nov. 9.

The TikToker debuted a fresh haircut, revealing a long bob.

After rocking platinum blonde tresses for years, Miley officially returned to her brunette roots to model Gucci's new collection.

The royal recently showed off her new curtain bangs during a public appearance on Sept. 27.